Common Symptoms of Hemolysis Signal the Underlying Threat of Serious Consequences
A patient may present with any of the common symptoms of PNH such as abdominal pain, dyspnea, or hemoglobinuria. But just like an iceberg hiding its true magnitude beneath the water, these symptoms may be indicative of more serious consequences that lie beneath the surface, such as thrombosis, pulmonary hypertension, or chronic kidney disease.
If a patient exhibits any of the early presenting symptoms, consider therapeutic intervention as this may help to avoid or delay more serious downstream complications of PNH.
The current availability of an effective PNH treatment option warrants testing appropriate patients.