Curative Therapy
Bone marrow transplantation
Bone marrow transplantation (BMT) is the only known treatment that may cure PNH. It involves replacing the body’s defective blood stem cells (cells produced in bone marrow that can become red blood cells, white blood cells, or platelets) with new, healthy ones. The healthy cells may be obtained from a close relative, such as a brother or sister, or from an unrelated donor.1
Bone marrow transplantation is typically only considered when other therapy options have failed. All BMTs carry significant risks, which you should discuss with your doctor and consider carefully. Only you and your doctor can decide whether BMT is right for you.
