Aplastic Anemia (AA)

Approximately 70% of patients with AA have PNH cells*¹:

• The number of PNH cells may increase rapidly and unpredictably over time^2,3
• In patients with AA, the presence of PNH cells can positively impact response to immunosuppressive therapy^1,4

Refractory Anemia Myelodysplastic Syndrome

Patients With Myelodysplastic Syndromes (MDS) Should Be Tested for PNH, as Recommended by NCCN Guidelines⁵

Select MDS subgroups are more likely to present with a PNH granulocyte clone¹

• Interim analysis shows that 17% of patients with refractory anemia-MDS (RA-MDS) have PNH granulocyte clones, as identified by high-sensitivity flow cytometry*¹

*0.01% PNH cell threshold.

Evaluate Your Patients With AA or RA-MDS Using High-Sensitivity Flow Cytometry at Diagnosis and Annually^2,3

Next: PNH in Unexplained Cytopenias