Chronic Kidney Disease in Patients with PNH

Chronic Kidney Disease

64% of Patients With PNH Have Chronic Kidney Disease (CKD)1

  • Renal failure: cause of death in 8% to 18% of patients with PNH2
  • Renal insufficiency prevalence in PNH is 6.6x higher than reported for the general population1,3
  • 80% of patients with PNH had renal hemosiderosis (median age 32)4

Next: Pulmonary Hypertension

1. Hillmen P, Elebute MO, Kelly R, et al. [ASH abstract]. Blood. 2007;110: Abstract 3678.
2. Nishimura J-I, Kanakura Y, Ware RE, et al. Medicine. 2004;83:193-207. 3. Stevens LA, Coresh J, Greene T, Levey AS. N Engl J Med. 2006;354:2473-2483. 4. Hill A, Reid SA, Rother RP, et al. [ASH abstract]. Blood. 2006;108: Abstract 979.