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Pulmonary Hypertension
Dyspnea May Be a Common Indicator of Pulmonary Hypertension (PHT)1
Nearly 50% of Patients With PNH Have Evidence of PHT1
- The majority of patients, 66%, reported dyspnea
- 72% of patients qualified dyspnea as moderate to severe2
- 88% reported distress due to dyspnea2
- Degree of dyspnea may be independent of hemoglobin level1
- PHT can be linked to hemolysis and resulting nitric oxide (NO) depletion3
Next: Impaired Quality of Life
1. Hill A, Rother RP, Wang X, et al. Br J Haematol. doi:10.1111/j.1365-2141.2010.08096.x.
2. Meyers G, Weitz I, Lamy T, et al. Blood. 2007;110: Abstract 3683. 3. Hill A, Wang X, Sapsford RJ, et al. Blood. 2005;106: Abstract 1046.
2. Meyers G, Weitz I, Lamy T, et al. Blood. 2007;110: Abstract 3683. 3. Hill A, Wang X, Sapsford RJ, et al. Blood. 2005;106: Abstract 1046.
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Dr Wendell Rosse discussing the risk of pulmonary hypertension in PNH.
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