Clinical Manifestations

Common symptoms in a patient with PNH can be manifestations of devastating consequences from intravascular hemolysis1,2


Listen to Wendell Rosse, MD, talk about the need to explain to patients with PNH about the progressive and chronic nature of their disease.

Contact a registered nurse from OneSource™ who can provide information and helpful tools to help you care for your patient with PNH.

Do you have any questions about PNH? Contact a medical expert for more information.

References: 1. Rachidi S, Musallam KM, Taher AT. Eur J Intern Med. 2010;21:260-267. 2. Borowitz MJ, Craig FE, DiGiuseppe JA, et al; for Clinical Cytometry Society. Cytometry Part B. 2010;78B:211-230. 3. Hillmen P, Elebute M, Kelly R, et al. Am J Hematol. 2010;85:553-559. 4. Kelly R, Richards S, Hillmen P, et al. Ther Clin Risk Manag. 2009;5:911-921. 5. Hill A, Sapsford RJ, Scally A, et al. Br J Haematol. 2012;158:409-414. 6. Hillmen P, Muus P, Dührsen U, et al. Blood. 2007;110:4123-4128. 7. Adams T, Fleischer D, Marino G, et al. Dig Dis Sci. 2002;47:58-64. 8. Brodsky RA. In: Hoffman R, Benz EJ Jr, Shattil SJ, et al, eds. Hematology: Basic Principles and Practice. 4th ed. Philadelphia, PA: Elsevier Churchill Livingstone; 2005:419-427.